HCID 23337314, compound → HCID 23337317, compound

HRID 903003Notes

Reaction equation

HRID 903003 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[N:11]1[CH2:15][CH:14]([CH3:16])[O:13][C:12]1=[O:17].[H][H]>[Pd].O1CCCC1>[NH2:8][C:6]1[CH:5]=[CH:4][C:3]([N:11]2[CH2:15][CH:14]([CH3:16])[O:13][C:12]2=[O:17])=[C:2]([Cl:1])[CH:7]=1

Participants

5

Reactant 2

HCID 23337314HCID 23337314, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 23337317HCID 23337317, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

A solution of 16.5 g of 2B and 0.5 g of 10% palladium-on-carbon catalyst in 200 ml of tetrahydrofuran was treated with hydrogen in a Parr shaker, giving 3-(4-amino-2-chlorophenyl)-5-methyl-2-oxazolidinone (2C), as a white solid, mp: 140°-141° C.

Sources & evidence

ORD record
ord-975ef08e66b544d99e582932b8b1b5cd
Source dataset
uspto-grants-1980_10
Patent number
US04226612

Reaction notes

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