Hydrochloric Acid → 2[1-(4-Fluorophenyl)-5-pyrazolyl] amino-2-imidazoline

HRID 903065Notes

Reaction equation

HRID 903065 reaction equation
C([N:4]1[CH2:8][CH2:7][N:6]=[C:5]1[NH:9][C:10]1[N:14]([C:15]2[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=2)[N:13]=[CH:12][CH:11]=1)(=O)C.Cl>CO>[F:21][C:18]1[CH:17]=[CH:16][C:15]([N:14]2[C:10]([NH:9][C:5]3[NH:6][CH2:7][CH2:8][N:4]=3)=[CH:11][CH:12]=[N:13]2)=[CH:20][CH:19]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 127637971-Acetyl-2[1-(4-fluorophenyl)-5-pyrazolyl]amino-2-imidazoline

Product 1

HCID 127638192[1-(4-Fluorophenyl)-5-pyrazolyl] amino-2-imidazoline

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1-Acetyl-2[1-(4-fluorophenyl)-5-pyrazolyl] amino-2-imidazoline (17.13 g.) was treated with HCl in methanol as described in Example II to give 12.06 g. product. mp 195°-197°

Workup

  1. customto give 12.06 g

Sources & evidence

ORD record
ord-7b034723edec4fd689d121aabcf81a1a
Source dataset
uspto-grants-1980_10
Patent number
US04226773

Reaction notes

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