Benzenamine hydrochloride (1:1) → HCID 73828564, compound

HRID 903113Notes

Reaction equation

HRID 903113 reaction equation
[Na].[CH:2]([CH:4]([CH2:7][NH:8][CH:9]=[O:10])[C:5]#[N:6])=O.Cl.[NH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>CO>[NH:12]([CH:2]=[C:4]([CH2:7][NH:8][CH:9]=[O:10])[C:5]#[N:6])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 8870Benzenamine hydrochloride (1:1)HCID 5360545SodiumHCID 21541183HCID 21541183, compound

Product 1

HCID 73828564HCID 73828564, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

74 parts of 75 percent pure sodium salt of α-formyl-β-formylaminopropionitrile are refluxed for 1 hour with 58.3 parts of aniline hydrochloride in 400 parts by volume of methanol, the reaction mixture is filtered, and the filtrate is concentrated to half its volume. 59.6 parts of α-anilinomethylene-β-formylaminopropionitrile are obtained, followed by a further 6.3 parts after concentrating the mother liquor; this corresponds in total to 87.4% of theory, based on the Na salt.

Workup

  1. filtrationthe reaction mixture is filtered
  2. concentrationthe filtrate is concentrated to half its volume

Sources & evidence

ORD record
ord-79db62d71d8946faa78544ea0cdfc50e
Source dataset
uspto-grants-1980_10
Patent number
US04226799

Reaction notes

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