Methyl Isocyanate → HCID 13420167, compound

HRID 903133Notes

Reaction equation

HRID 903133 reaction equation
[F:1][C:2]([F:15])([F:14])[C:3]1[CH:13]=[CH:12][CH:11]=[CH:10][C:4]=1[O:5][CH:6]1[CH2:9][NH:8][CH2:7]1.[CH3:16][N:17]=[C:18]=[O:19]>C1C=CC=CC=1>[CH3:16][NH:17][C:18]([N:8]1[CH2:9][CH:6]([O:5][C:4]2[CH:10]=[CH:11][CH:12]=[CH:13][C:3]=2[C:2]([F:1])([F:14])[F:15])[CH2:7]1)=[O:19]

Participants

4

Reactant 2

HCID 12228Methyl IsocyanateHCID 128125053-[2-(Trifluoromethyl)phenoxy]azetidine

Product 1

HCID 13420167HCID 13420167, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

To a stirring solution of 3-(2-trifluoromethylphenoxy) azetidine (4.5 g., 0.02 mole) in 50 ml. of dry benzene was added slowly at room temperature 1.2 g. (0.02 mole) of methylisocyanate. After an additional 30 minutes a solid separated which was collected and recrystallized from benzene. The product (3.5 g., 68%) melted at 134°-136° C.

Workup

  1. customAfter an additional 30 minutes a solid separated which
  2. customwas collected
  3. customrecrystallized from benzene

Sources & evidence

ORD record
ord-6ab3cd699c274f039b258f156f05e8aa
Source dataset
uspto-grants-1980_10
Patent number
US04226861

Reaction notes

Loading…