Methyl Isocyanate → HCID 13420169, compound

Participants

Reaction Steps

To a stirring solution of 5.0 g. (0.026 mole) of 4-(3-azetidinyloxy)benzamide in 75 ml. of dry benzene was added dropwise 1.5 g. (0.026 mole) of methylisocyanate. Stirring was continued for 1.5 hours. The white solid which separated was filtered and recrystallized using 95% ethanol. The solid was triturated with acetonitrile (due to solvation effects of the ethanol). The product weighed 4.0 g. (58%) and melted at 208°-210° C.

Provenance & Evidence