反应详情

A mixture of 2.8 g. of 7,10-dichloro-2-methoxypyrido[3,2-b]quinoline, 1.5 g. of 4-diethylaminobutylamine and 6.5 g. of phenol is heated at 100° C. for 3 hours. The reaction is cooled, 20 ml. of ethanol is added and this mixture is poured into a mixture of 200 ml. of acetone and 2.5 ml. of concentrated hydrochloric acid. The yellow solic is collected, air-dried and recrystallized from ethanol, giving the desired product, mp. 246°-274° C. (dec.).

1. additionA mixture of 2.8 g
2. temperatureThe reaction is cooled
3. additionthis mixture is poured into a mixture of 200 ml
4. customThe yellow solic is collected
5. customair-dried
6. customrecrystallized from ethanol