Imidazole → HCID 23337927, compound

HRID 903164Notes

Reaction equation

HRID 903164 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.Br[C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][C:15]#[N:16])=[CH:9][CH:8]=1.C(=O)([O-])[O-].[K+].[K+]>[N+](C1C=CC=CC=1)([O-])=O>[N:1]1([C:7]2[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][C:15]#[N:16])=[CH:9][CH:8]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

5

Reactant 3

HCID 795ImidazoleHCID 11430Potassium CarbonateHCID 27356113-(4-Bromophenyl)propionitrile

Product 1

HCID 23337927HCID 23337927, compound

Reagents, catalysts & solvents 1

HCID 7416NitrobenzeneSolvent

Conditions

Temperature
160 °C

Procedure

A mixture of 2.8 g of imidazole, 7.6 g of 3-(p-bromophenyl)propionitrile, 4.7 g of anhydrous potassium carbonate, and 0.4 g of cuprous bromide in 15 ml of nitrobenzene was heated at 160° C. for 25 hours under stirring.

Sources & evidence

ORD record
ord-21b1c048480943a9b2344229bc5f6544
Source dataset
uspto-grants-1980_10
Patent number
US04226878

Reaction notes

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