HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903170Generated: October 31, 2026
2-{[2-Chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acid → HCID 15313948, compound
https://huagongshe.com/reaction/903170
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-{[2-Chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acid | HCID 3947643 | — |
| Reactant | HCID 20285866 | HCID 20285866 | — |
| Reactant | Cyano[6-(4-fluorophenoxy)-2-pyridyl]methanol | HCID 20293447 | — |
| Reactant | HCID 23337856 | HCID 23337856 | — |
| Reactant | HCID 23337863 | HCID 23337863 | — |
| Reactant | HCID 23470896 | HCID 23470896 | — |
| Reactant | HCID 54317032 | HCID 54317032 | — |
| Reactant | HCID 54355766 | HCID 54355766 | — |
| Reactant | HCID 54357152 | HCID 54357152 | — |
| Reactant | Cyano[6-(4-methylphenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate | HCID 54530615 | — |
| Reactant | HCID 70593611 | HCID 70593611 | — |
| Reactant | HCID 131711911 | HCID 131711911 | — |
| Product | HCID 15313948 | HCID 15313948 | — |
Reaction Steps
By the above procedure, each of cyano[6-(4-fluorophenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate, cyano[6-(4-methylphenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate, cyano[6-(4-methoxyphenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate, cyano[6-(4-chlorophenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate, cyano[6-(methylthiophenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate, and cyano[6-(4-trifluoromethylphenoxy)-2-pyridyl)]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate is prepared by the reaction of the acid chloride of 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoic acid with each of cyano[6-(4-fluorophenoxy)-2-pyridyl]methanol, cyano[6-(4-methylphenoxy)-2-pyridyl]methanol, cyano[6-(4-methoxyphenoxy)-2-pyridyl]methanol, cyano[6-(4-chlorophenoxy)-2-pyridyl]methanol, cyano[6-(4-methylthiophenoxy)-2-pyridyl]methanol and cyano[6-(4-trifluoromethylphenoxy)-2-pyridyl]methanol, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04226872 |
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| Source dataset | uspto-grants-1980_10 |
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| ORD ID | ord-a98f46b544d64e29ba4b07d6c50df1af |
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| Source note | uspto-grants-1980_10 |
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