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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903171Generated: October 26, 2026

2-{[2-Chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acid → [6-(4-Fluorophenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate

https://huagongshe.com/reaction/903171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-{[2-Chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acidHCID 3947643—
Reactant[6-(4-Fluorophenoxy)-2-pyridyl]methanolHCID 20285867—
Product[6-(4-Fluorophenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoateHCID 23337845—

Reaction Steps

The acid chloride of 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoic acid is reacted with [6-(4-fluorophenoxy)-2-pyridyl]methanol using the procedure of Example 1 to give [6-(4-fluorophenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04226872
Source datasetuspto-grants-1980_10
ORD IDord-176fb71ae6a44f11ade06e353acc5fb2
Source noteuspto-grants-1980_10