Water → Sulfate Ion

HRID 903184Notes

Reaction equation

HRID 903184 reaction equation
[S:1]([OH:5])([OH:4])(=[O:3])=[O:2].[NH2:6][NH:7][C:8]([NH2:10])=[NH:9].O.[Cl:12][C:13]1[CH:22]=[CH:21][CH:20]=[CH:19][C:14]=1[O:15][CH2:16][CH:17]=O>C(O)(=O)C.C(O)C>[C:8]([NH:7][N:6]=[CH:17][CH2:16][O:15][C:14]1[CH:19]=[CH:20][CH:21]=[CH:22][C:13]=1[Cl:12])(=[NH:10])[NH2:9].[S:1]([O-:5])([O-:4])(=[O:3])=[O:2]

Participants

7

Reactant 3

HCID 962WaterHCID 148160092-(2-Chlorophenoxy)acetaldehydeHCID 178513188HCID 178513188, compound

Product 2

HCID 1117Sulfate IonHCID 178513163HCID 178513163, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidCatalystHCID 702EthanolSolvent

Procedure

A solution of 3.3 g of aminoguanidine sulphate in 30 ml. of water is added to a solution of 2.8 g. of o-chlorophenoxy acetaldehyde in 30 ml. of ethyl alcohol at 95°. Heating is effected under reflux for 4 hours, with addition of a few drops of acetic acid. After cooling, a solid product precipitates and it is separated and washed with very little water followed by ethanol. Recrystallisation is effected in the water-ethanol mixture (1/1). The o-chlorophenoxy acetaldehyde guanyl hydrazone is obtained in the form of sulphate, m.p.=198° C., with a yield of 90%.

Workup

  1. customat 95°
  2. temperatureHeating
  3. temperatureAfter cooling
  4. customa solid product precipitates
  5. customit is separated
  6. washwashed with very little water
  7. customRecrystallisation

Sources & evidence

ORD record
ord-520e8dd145894884b05ee3022550e0ed
Source dataset
uspto-grants-1980_10
Patent number
US04226885

Reaction notes

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