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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903190Generated: October 27, 2026

Acetyl chloride → 1-(Benzyloxycarbonyldiethylphosphono)methyl-3-azido-4-chloro-2-azetidinone

https://huagongshe.com/reaction/903190

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
Reactant1-(Benzyloxycarbonyldiethylphosphono)methyl-3-azido-4-methylsulfonyl-2-azetidinoneHCID 86737251—
Product1-(Benzyloxycarbonyldiethylphosphono)methyl-3-azido-4-chloro-2-azetidinoneHCID 86737253—

Reaction Steps

1-(Benzyloxycarbonyldiethylphosphono)methyl-3-azido-4-methylsulfonyl-2-azetidinone (0.446 g.) is dissolved in acetyl chloride (5 ml.). The mixture is allowed to stand for 10 minutes and the acetyl chloride is removed under reduced pressured to afford 1-(benzyloxycarbonyldiethylphosphono)methyl-3-azido-4-chloro-2-azetidinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04226866
Source datasetuspto-grants-1980_10
ORD IDord-14df11bc91e64d2684f62d28aeb987fc
Source noteuspto-grants-1980_10