HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → HCID 23338131, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | Cyclohexanecarbonyl chloride, 5-methyl-2-(1-methylethyl)- | HCID 13734319 | — |
| Reactant | 4-Aminobut-2-yn-1-ol hydrochloride | HCID 19775531 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 23338131 | HCID 23338131 | — |
Reaction Steps
Sodium bicarbonate (2.5 g.) and 4-aminobut-2-yn-1-ol hydrochloride (2.5 g.) were dissolved in water (60 ml.) and a solution of p-menth-3-oyl chloride in ether (100 ml.) added. The mixture was stirred vigorously for two hours and the ether layer separated and dried over MgSO4. Evaporation of the ether gave N-(4-hydroxybut-2-ynyl)-p-menthane-3-carboxamide as a very viscous liquid: b.p. 180°/0.1 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04226988 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-e4b4a08453fc4b79b9d8a36a715ddc74 |
| Source note | uspto-grants-1980_10 |