HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(5,6-Dimethyl-3-pyridylmethyl)-2-nitroamino4-pyrimidone → HCID 20279286, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(5,6-Dimethyl-3-pyridylmethyl)-2-nitroamino4-pyrimidone | HCID 12783831 | — |
| Reactant | 4-(3-Methoxypyridin-2-yl)butan-1-amine | HCID 13060028 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20279286 | HCID 20279286 | — |
Reaction Steps
Equimolar amounts of 5-(5,6-dimethyl-3-pyridylmethyl)-2-nitroamino-4-pyrimidone and 4-(3-methoxy-2-pyridyl)butylamine were heated together under reflux in ethanol for 24 hours. An additional 0.1 molar equivalent of the amine was added and the mixture was heated under reflux for a further 24 hours, evaporated to dryness and purified to give 2-[4-(3-methoxy-2-pyridyl)butylamino]-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone dihydrate, m.p. 93°-94°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04227000 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-8a9e3dd4f4fa48b6bc730d2d22263871 |
| Source note | uspto-grants-1980_10 |