huagongshe.com
HRID903377

反应详情

EQUATION

反应方程式

HRID 903377 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(Cc2cnc(N[N+](=O)[O-])[nH]c2=O)cn1
HCID12783832

未命名化合物

结构：NCCSCc1nccs1
HCID12923403

2-{[(1,3-Thiazol-2-yl)methyl]sulfanyl}ethan-1-amine

C6H10N2S2

PRODUCTS

生成物

1
结构：COc1ccc(Cc2cnc(NCCSCc3nccs3)[nH]c2=O)cn1
HCID12799559

未命名化合物

收率 60%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

An equimolar mixture of 2-nitroamino-5-(6-methoxy-3-pyridylmethyl)-4-pyrimidone and 2-(2-thiazolylmethylthio)ethylamine was heated under reflux in ethanol for 18 hours. The solid which crystallised out on cooling was recrystallised from ethanol to give 2-[2-(2-thiazolylmethylthio)ethylamino]-5-(6-methoxy-3-pyridylmethyl)-4-pyrimidone, m.p. 95°-7°, in 60% yield.

WORKUP

后处理

  1. temperaturewas heated
  2. customThe solid which crystallised out
  3. temperatureon cooling
  4. customwas recrystallised from ethanol