Hydrochloric Acid → HCID 23336328, compound

HRID 903527Notes

Reaction equation

HRID 903527 reaction equation
Cl[O-].[Na+].[CH2:4]([O:6][P:7]([O:17][CH2:18][CH3:19])([CH2:9][C:10]([O:12][CH:13]([CH3:16])[CH2:14][CH3:15])=[O:11])=[O:8])[CH3:5].[ClH:20].C(Cl)(Cl)(Cl)[Cl:22]>>[Cl:20][C:9]([Cl:22])([P:7]([O:6][CH2:4][CH3:5])([O:17][CH2:18][CH3:19])=[O:8])[C:10]([O:12][CH:13]([CH3:16])[CH2:14][CH3:15])=[O:11]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 5943Carbon Tetrachloride2×HCID 23336325HCID 23336325, compoundHCID 23665760Sodium Hypochlorite

Product 1

HCID 23336328HCID 23336328, compound

Conditions

Temperature
0 °C

Procedure

A mixture of 185 ml of 5.25% commercial grade sodium hypochlorite solution (Clorox®) and 100 ml of carbon tetrachloride was cooled to 0° C. To this mixture, with vigorous stirring, was added a solution of 12.6 g of 1-methylpropyl 2-(diethoxyphosphinyl)-acetate in 50 ml of carbon tetrachloride over a 1/2 hour period. During this addition the temperature was kept at 0°-5° and the pH at 9.0-9.5 by the simultaneous addition of 1 N hydrochloric acid. The reaction mixture was stirred an additional 15 minutes at 0°-5° C. The carbon tetrachloride layer was washed with water, dried over magnesium sulfate and stripped at 60° C./1 mm pressure to yield 16.0 g of 1-methylpropyl 2,2-dichloro-2-(diethoxyphosphinyl)acetate as a pale yellow oil ND27 =1.4524.

Workup

  1. additionDuring this addition the temperature
  2. customwas kept at 0°-5°
  3. washThe carbon tetrachloride layer was washed with water
  4. dry with materialdried over magnesium sulfate
  5. customstripped at 60° C.

Sources & evidence

ORD record
ord-fe9d2395428340d8a6e956a4457f55a7
Source dataset
uspto-grants-1980_10
Patent number
US04228109

Reaction notes

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