HCID 12823194, compound → HCID 23336598, compound

Participants

Reaction Steps

A suspension of N-acetyl-7-chloro-8-mercapto-1,2,3,4-tetrahydroisoquinoline (1 g., 0.004 m.) in dilute hydrochloric acid was refluxed for three hours under an argon atmosphere. The reaction mixture was evaporated under reduced pressure and the residue was dried by evaporation from methanol-toluene. Recrystallization from methanol-ethyl acetate gave 7-chloro-8-mercapto-1,2,3,4-tetrahydroisoquinoline hydrochloride, m.p. 205°-207° C.

Provenance & Evidence