HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 23336737, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phosphoric Acid | HCID 1004 | — |
| Reactant | Isoprene | HCID 6557 | — |
| Reactant | 3-Chloro-o-cresol | HCID 14856 | — |
| Catalyst | Phenothiazine | HCID 7108 | — |
| Solvent | 1,2-Dichlorobenzene | HCID 7239 | — |
| Product | HCID 23336737 | HCID 23336737 | 24.1% |
Reaction Steps
437 g of isoprene stabilized with 1.3 g of phenothiazine were added dropwise in the course of 6 hours to a solution of 832 g of 3-chloro-2-methyl-phenol, 74.4 g of 85% strength phosphoric acid and 5.8 ml of water in 1.4 liters of o-dichlorobenzene at 110° C. To complete the reaction, stirring was continued overnight at 110° C. The acid phase was separated off and the organic phase was washed until neutral. Fractional distillation gave 296 g of 7-chloro-5-hydroxy-3,3,6-trimethyl-indan; boiling point: 161°-164° C./11 mm Hg; melting point: 109°-109.5° C. ##STR8##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04228181 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-5d3c20d2a7994d4eaf7e1481549dc7dd |
| Source note | uspto-grants-1980_10 |