Tryptamine → HCID 384617, compound

HRID 903590Notes

Reaction equation

HRID 903590 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[NH:6][CH:5]=1.[CH:13]1([C:19](Cl)=[O:20])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1>>[CH:13]1([C:19]([NH:1][CH2:2][CH2:3][C:4]2[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[NH:6][CH:5]=2)=[O:20])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1

Participants

3

Reactant 2

HCID 1150TryptamineHCID 75938Cyclohexanecarbonyl chloride

Product 1

HCID 384617HCID 384617, compoundYield 81.2%

Procedure

10 g of tryptamine and 10 g of cyclohexylcarbonyl chloride were treated in the same manner as described in Example 4-(1). 13.7 g of N-cyclohexylcarbonyl-tryptamine (i.e., 3-(2-cyclohexylcarbonylaminoethyl)-indole) were thereby obtained. Yield: 81.2%

Sources & evidence

ORD record
ord-38c4714f26d34c2a9aaa553a0932efc8
Source dataset
uspto-grants-1980_10
Patent number
US04228168

Reaction notes

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