HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 70582839, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 3-Pyridinecarbonyl chloride, hydrochloride (1:1) | HCID 88438 | — |
| Reactant | HCID 57212445 | HCID 57212445 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 70582839 | HCID 70582839 | — |
Reaction Steps
Equimolar amounts of 17-cyclopropylmethyl-3,14β-dihydroxy-6-oxamorphinan (XVI), nicotinoyl chloride hydrochloride and pyridine are mixed together in dry methylene chloride and the mixture is heated at reflux for 3 hours to produce the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04228285 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-85f2ce482bcf4c7284e23cad7fb05f71 |
| Source note | uspto-grants-1980_10 |