化工社化工社 化学情報印刷レポート · 研究参考用
Sulfate Ion → 3-[(2-Aminoethyl)thiomethyl]pyridazine dipicrate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfate Ion | HCID 1117 | — |
| 反応物 | 3-(Hydroxymethyl)pyridazine | HCID 2794575 | — |
| 反応物 | Picrate | HCID 4432340 | — |
| 反応物 | 3-[(2-Aminoethyl)thiomethyl]pyridazine | HCID 20242505 | — |
| 生成物 | 3-[(2-Aminoethyl)thiomethyl]pyridazine dipicrate | HCID 86737273 | — |
| 生成物 | HCID 178513026 | HCID 178513026 | — |
反応手順
By the procedure of Example 1, using 3-hydroxymethylpyridazine, the intermediate 3-[(2-aminoethyl)thiomethyl]pyridazine dipicrate, m.p. 145°-148° is prepared. Converting this picrate to the dihydrobromide, then to the free base by the procedure of Example 1 and reacting the 3-[(2-aminoethyl)thiomethyl]pyridazine with S-methylsiothiouronium sulphate by the procedure of Example 1 gives the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04228291 |
| 出典データセット | uspto-grants-1980_10 |
| ORD ID | ord-fc36eafd42d14dd386759eccec607015 |
| 出典メモ | uspto-grants-1980_10 |