Cysteamine → 4-[(2-Aminoethyl)thiomethyl]-1,2,3-thiadiazole

HRID 903776Notes

Reaction equation

O[CH2:2][C:3]1[N:4]=[N:5][S:6][CH:7]=1.[NH2:8][CH2:9][CH2:10][SH:11]>>[NH2:8][CH2:9][CH2:10][S:11][CH2:2][C:3]1[N:4]=[N:5][S:6][CH:7]=1

Participants

Reactant 2

HCID 6058Cysteamine

HCID 147274091,2,3-Thiadiazol-4-ylmethanol

Product 1

HCID 204020654-[(2-Aminoethyl)thiomethyl]-1,2,3-thiadiazole

Procedure

Reacting 4-hydroxymethyl-1,2,3-thiadiazole with cysteamine by the procedure of Example 1 gives 4-[(2-aminoethyl)thiomethyl]-1,2,3-thiadiazole. From this compound by the procedures of Examples 1,2 and 3, the following products are prepared:

Sources & evidence

ORD record: ord-43be73dd48b046469db55cab89030bce
Source dataset: uspto-grants-1980_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04228291

Reaction notes

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