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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903778Generated: October 26, 2026

N-3-Bromopropylphthalimide → 3-(3-Aminopropylamino)-1,2,4-thiadiazole

https://huagongshe.com/reaction/903778

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-3-BromopropylphthalimideHCID 21611—
Reactant1,2,4-Thiadiazol-3-amineHCID 20249664—
Product3-(3-Aminopropylamino)-1,2,4-thiadiazoleHCID 20557655—

Reaction Steps

Reaction of 3-amino-1,2,4-thiadiazole with 3-phthalimidopropyl bromide and hydrazinolysis of the product gives 3-(3-aminopropylamino)-1,2,4-thiadiazole and from this intermediate N-cyano-N'-methyl-N"-[3-(3-(1,2,4-thiadiazolyl)amino)propyl]-guanidine is prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04228291
Source datasetuspto-grants-1980_10
ORD IDord-ce2a51f12e3945078ac3869bd89562fc
Source noteuspto-grants-1980_10