HRID903836

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14457404

未命名化合物

HCID19754841

未命名化合物

HCID53885514

未命名化合物

PRODUCTS

生成物

结构：C#CC(OC(=O)C(C=Cc1ccc(F)cc1)C(C)C)c1ccc(F)c(Oc2ccccc2)c1

HCID54345861

未命名化合物

结构：CC(OC(=O)C(C=Cc1ccc(F)cc1)C(C)C)c1ccc(F)c(Oc2ccccc2)c1

HCID54357547

未命名化合物

PROCEDURE

实验过程

Each of α-ethynyl-4-fluoro-3-phenoxybenzyl alcohol and 4-fluoro-α-methyl-3-phenoxybenzyl alcohol is reacted with 4-(4-fluorophenyl)-2-isopropyl-3-butenoic acid to yield α-ethynyl-4-fluoro-3-phenoxybenzyl 4-(4-fluorophenyl)-2-isopropyl-3-butenoate and 4-fluoro-α-methyl-3-phenoxybenzyl 4-(4-fluorophenyl)-2-isopropyl-3-butenoate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-13d1faefb17e44c99a514b5950c154f9
来源数据集: uspto-grants-1980_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04229368
来源说明: uspto-grants-1980_10

反应 SMILES

[C:1]([CH:3]([OH:18])[C:4]1[CH:9]=[CH:8][C:7]([F:10])=[C:6]([O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:5]=1)#[CH:2].[F:19][C:20]1[CH:28]=[CH:27][C:23]([CH:24]([OH:26])[CH3:25])=[CH:22][C:21]=1[O:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1.[F:36][C:37]1[CH:42]=[CH:41][C:40]([CH:43]=[CH:44][CH:45]([CH:49]([CH3:51])[CH3:50])[C:46](O)=[O:47])=[CH:39][CH:38]=1>>[F:36][C:37]1[CH:38]=[CH:39][C:40]([CH:43]=[CH:44][CH:45]([CH:49]([CH3:51])[CH3:50])[C:46]([O:18][CH:3]([C:1]#[CH:2])[C:4]2[CH:9]=[CH:8][C:7]([F:10])=[C:6]([O:11][C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH:5]=2)=[O:47])=[CH:41][CH:42]=1.[F:36][C:37]1[CH:38]=[CH:39][C:40]([CH:43]=[CH:44][CH:45]([CH:49]([CH3:51])[CH3:50])[C:46]([O:26][CH:24]([CH3:25])[C:23]2[CH:27]=[CH:28][C:20]([F:19])=[C:21]([O:29][C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)[CH:22]=2)=[O:47])=[CH:41][CH:42]=1