Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903836Generated: October 31, 2026

alpha-Ethynyl-4-fluoro-3-phenoxybenzyl alcohol → alpha-Ethynyl-4-fluoro-3-phenoxybenzyl 4-(4-fluorophenyl)-2-isopropyl-3-butenoate

https://huagongshe.com/reaction/903836

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha-Ethynyl-4-fluoro-3-phenoxybenzyl alcoholHCID 14457404—
Reactant1-(4-Fluoro-3-phenoxyphenyl)ethanolHCID 19754841—
Reactant2-Isopropyl-4-(4-fluorophenyl)-3-butenoic acidHCID 53885514—
Productalpha-Ethynyl-4-fluoro-3-phenoxybenzyl 4-(4-fluorophenyl)-2-isopropyl-3-butenoateHCID 54345861—
Product4-Fluoro-alpha-methyl-3-phenoxybenzyl 4-(4-fluorophenyl)-2-isopropyl-3-butenoateHCID 54357547—

Reaction Steps

Each of α-ethynyl-4-fluoro-3-phenoxybenzyl alcohol and 4-fluoro-α-methyl-3-phenoxybenzyl alcohol is reacted with 4-(4-fluorophenyl)-2-isopropyl-3-butenoic acid to yield α-ethynyl-4-fluoro-3-phenoxybenzyl 4-(4-fluorophenyl)-2-isopropyl-3-butenoate and 4-fluoro-α-methyl-3-phenoxybenzyl 4-(4-fluorophenyl)-2-isopropyl-3-butenoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04229368
Source datasetuspto-grants-1980_10
ORD IDord-13d1faefb17e44c99a514b5950c154f9
Source noteuspto-grants-1980_10