HCID 23335449, compound → HCID 131711917, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2.19 g of the obtained 3-(3,5-dichlorophenylthiocarbamoyl)thiazolidine-2-carboxylic acid ethyl ester and 20 ml of concentrated hydrochloric acid was stirred at 120° C. for 1.5 hours. After the reaction mixture was cooled, the precipitate was separated, followed by recrystallization from a mixed solvent of ethyl acetate and n-hexane to give 1.43 g (yield 74.7%) of 6-(3,5-dichlorophenyl)perhydroimidazo[5,1-b]thiazole-5-thion-7-on (Compound No. 2). The resulting point and the elementary analysis were as given in table 1.

Provenance & Evidence