1-Methylpiperazine → 1-(2,5-Difluorobenzyl)-7-[4-(4-methylpiperazine-1-carbonyl)phenyl]-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one

HRID 90400Notes

Reaction equation

HRID 90400 reaction equation
[CH3:30][N:31]1[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]1.[F:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:12][cH:13][c:14](-[c:16]4[cH:17][cH:18][c:19]([C:20](=[O:21])[OH:22])[cH:23][cH:24]4)[cH:15]3)[NH:8][CH2:9][C:10]2=[O:11])[cH:25][c:26]([F:29])[cH:27][cH:28]1>>[F:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:12][cH:13][c:14](-[c:16]4[cH:17][cH:18][c:19]([C:20](=[O:22])[N:34]5[CH2:33][CH2:32][N:31]([CH3:30])[CH2:36][CH2:35]5)[cH:23][cH:24]4)[cH:15]3)[NH:8][CH2:9][C:10]2=[O:11])[cH:25][c:26]([F:29])[cH:27][cH:28]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 24853017HCID 24853017, compound

Product 1

HCID 248531241-(2,5-Difluorobenzyl)-7-[4-(4-methylpiperazine-1-carbonyl)phenyl]-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one

Sources & evidence

ORD record
ord-d684bcb09f064c42b7c6271409cfa70e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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