反应详情

α-Amino(2,3-dihydro-5-benzofuranyl)acetic acid (192 mg, 1 mmole) is added to 10 ml of 1:1 dioxane-water mixture with 4 mM of triethylamine and 0.17 ml of tert-butoxycarbonylazide. This mixture is stirred overnight at room temperature. The mixture is diluted with water and extracted with chloroform. The chloroform is dried and evaporated. The residue is taken up in ethyl acetate and washed with dilute aqueous hydrochloric acid. The organic layer is dried over magnesium sulfate and evaporated to give the title compound in a yield of about 80%.

1. extractionextracted with chloroform
2. dry with materialThe chloroform is dried
3. customevaporated
4. washwashed with dilute aqueous hydrochloric acid
5. dry with materialThe organic layer is dried over magnesium sulfate
6. customevaporated