Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | alpha-Chlorosulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid | HCID 23335839 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 23335847 | HCID 23335847 | — |
Reaction Steps
α-Chlorosulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid (5 mmole) is added to 30 ml of ethyl ether. To this mixture is added 5 mmole of ethanol in 10 ml of ethyl ether which contains 10 mmole of triethylamine. The mixture is stirred at 20° C. for about 1 hour and 50 ml of water is added. The pH is adjusted to about 6.5 and the layers separated. The organic layer is dried over magnesium sulfate, filtered and evaporated to give α-ethoxysulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04229575 |
|---|
| Source dataset | uspto-grants-1980_10 |
|---|
| ORD ID | ord-9d335cd22e5647139676fd2f35ab14c9 |
|---|
| Source note | uspto-grants-1980_10 |
|---|
