HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylsulphamoyl chloride → HCID 20704038, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylsulphamoyl chloride | HCID 83372 | — |
| Reactant | 1,1,1,3,3,3-Hexafluoro-2-(4-(methylamino)phenyl)propan-2-OL | HCID 805015 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 20704038 | HCID 20704038 | — |
Reaction Steps
To 5.4 g (20 mmole) N-methyl-4-(hexafluoro-2-hydroxy-2-propyl)aniline in 50 ml pyridine add 4.3 g (30 mmole) dimethylsulfamoyl chloride. Stir 16 hours, pour onto water, acidify and extract with Et2O. Wash with 1N NaOH, acidify the aqueous layer, and extract with Et2O. Dry, concentrate and recrystallize first from CCl4, and then from Et2O-hexane to obtain the product; m.p. 63°-65° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230635 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-652893c945fb47a98e2a55df151411d4 |
| Source note | uspto-grants-1980_10 |