HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 23333787, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | 2-[(Dimethylamino)methyl]-6-methyl-3-pyridinol | HCID 23333794 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 23333787 | HCID 23333787 | 76.3% |
Reaction Steps
The procedure described in Example 1 was repeated except that 2-dimethylaminomethyl-3-hydroxy-6-methylpyridine (16.6 g.) and imidazole (6.8 g.) were reacted in xylene (50 ml.) to afford 2-(imidazol-1-ylmethyl)-3-hydroxy-6-methylpyridine (yield, 14.42 g.), m.p. 153°-155° C. after recrystallization from isopropanol/petroleum ether (b.p. 60°-80° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230714 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-06271c6cf729436fb963977e705f650a |
| Source note | uspto-grants-1980_10 |