HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 904156Generated: November 1, 2026
Water → 1-(4,6-Dimethyl-2-pyridinyl)-3-(tetrahydro-1-methyl-4-oxo-1H-imidazol-2-ylidene) urea
https://huagongshe.com/reaction/904156
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Amino-4,6-dimethylpyridine | HCID 21507 | — |
| Reactant | tetrahydro-1-methyl-4-oxo-1H-imidazol-2-ylidene carbamic acid | HCID 136469822 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-(4,6-Dimethyl-2-pyridinyl)-3-(tetrahydro-1-methyl-4-oxo-1H-imidazol-2-ylidene) urea | HCID 136438532 | 38% |
Reaction Steps
A mixture of 3.0 g (12.8 mM) of the phenyl carbamate 8, and 1.6 g (12.8 mM) of 4,6-dimethyl-2-aminopyridine in 50 ml of anhydrous DMF was heated at 55° C. for 8 hrs., cooled, and poured into 200 ml water. The resulting precipitate was collected and recrystallized from ethyl acetate to give 1.3 g of the above urea as a light yellow solid, m.p. 192°-193° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04230713 |
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| Source dataset | uspto-grants-1980_10 |
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| ORD ID | ord-372296f8c7bb4130a010076202f22300 |
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| Source note | uspto-grants-1980_10 |
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