Methanol → HCID 23333614, compound

HRID 904198Notes

Reaction equation

HRID 904198 reaction equation
[CH2:1]([N:4]1[CH2:10][C:9]2[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=2[C:7](=[O:15])[C:6]2[CH:16]=[C:17]([CH2:20][C:21]([O:23]C)=[O:22])[CH:18]=[CH:19][C:5]1=2)[CH2:2][CH3:3].[OH-].[Na+].CO>O>[CH2:1]([N:4]1[CH2:10][C:9]2[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=2[C:7](=[O:15])[C:6]2[CH:16]=[C:17]([CH2:20][C:21]([OH:23])=[O:22])[CH:18]=[CH:19][C:5]1=2)[CH2:2][CH3:3]

Participants

5

Reactant 3

HCID 887MethanolHCID 14798Sodium HydroxideHCID 23333586HCID 23333586, compound

Product 1

HCID 23333614HCID 23333614, compoundYield 79.4%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixed liquid of methyl 5,6-dihydro-5-n-propyl-11-oxodibenz[b,e]azepine-2-acetate (0.5 g), sodium hydroxide (2 g), methanol (20 ml) and water (10 ml) was treated in the same manner as described in Example 21 to afford the desired compound (0.38 g) as yellow powdery crystals.

Sources & evidence

ORD record
ord-3ec09ce6beae47b7b08d22ff54d225d3
Source dataset
uspto-grants-1980_10
Patent number
US04230703

Reaction notes

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