Hydrochloric Acid → HCID 70586442, compound

Participants

Reaction Steps

A suspension of 17-cyano-3-methoxy-8β-methylmorphinan-6-one (prepared in Part B) in 2 N HCl (1 g/30 ml) was refluxed for 8 hours. The resulting solution was evaporated to dryness, azeotroped several times with ethanol, and the crystalline residue suspended in ethanol and collected. The product was used without further purification. The yield of crystalline material, mp 204°-208° C., was 90%.

Provenance & Evidence