Hydrochloric Acid → HCID 70584891, compound

HRID 904212Notes

Reaction equation

HRID 904212 reaction equation
C([N:3]1[CH2:21][CH2:20][C@@:10]23[C:11]4[CH:12]=[C:13]([O:18][CH3:19])[CH:14]=[CH:15][C:16]=4[CH2:17][C@@H:4]1[C@@H:5]2[C@@H:6]([CH2:23][CH3:24])[CH2:7][C:8](=[O:22])[CH2:9]3)#N.[ClH:25]>>[ClH:25].[CH2:23]([C@@H:6]1[C@@H:5]2[C@:10]3([CH2:20][CH2:21][NH:3][C@@H:4]2[CH2:17][C:16]2[CH:15]=[CH:14][C:13]([O:18][CH3:19])=[CH:12][C:11]3=2)[CH2:9][C:8](=[O:22])[CH2:7]1)[CH3:24]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 86737292HCID 86737292, compound

Product 1

HCID 70584891HCID 70584891, compoundYield 72%

Procedure

A sample of 17-cyano-8β-ethyl-3-methoxymorphinan-6-one was treated with 2 N HCl as described in Example 1C. The product was isolated in 72% yield, mp 280° C.

Workup

  1. customThe product was isolated in 72% yield, mp 280° C.

Sources & evidence

ORD record
ord-86d13858750c45e0a88ff0c9519bb9d2
Source dataset
uspto-grants-1980_10
Patent number
US04230712

Reaction notes

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