Hydrochloric Acid → HCID 70585373, compound

Participants

Reaction Steps

A suspension of 17-cyano-3-methoxymorphinan-6-one (6.9 g; prepared in Part B) in 200 ml of 2 N HCl was refluxed for 8 hours. The resulting solution was treated as in Example 1C to yield 5.2 g of crystalline product, mp 190°-200° C. An additional 0.9 g was obtained from the mother liquor. Total yield was 6.1 g (85%).

Provenance & Evidence