HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Cyanide → 12-Hydroxydodecanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | 11-Bromo-1-undecanol | HCID 74163 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 12-Hydroxydodecanenitrile | HCID 10330348 | — |
Reaction Steps
A solution 4.6 g. of 11-bromoundecanol and 1.6 g. of sodium cyanide in 40 ml. of dimethylformamide is heated at 80° C. for 18 hours, cooled, and poured into ice-water. The mixture is extracted with methylene chloride and the extract is dried over anhydrous magnesium sulfate. Evaporation of the solution affords 12-hydroxydodecanonitrile as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230628 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-af4d2d2762314fcc986794205f24620b |
| Source note | uspto-grants-1980_10 |