HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine, 1-(2-chloroethyl)-, hydrochloride → 4-(2'-Piperidinoethoxy)-3-phenyl-coumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine, 1-(2-chloroethyl)-, hydrochloride | HCID 74826 | — |
| Reactant | Coumarin, 4-hydroxy-3-phenyl- | HCID 54688870 | — |
| Product | 4-(2'-Piperidinoethoxy)-3-phenyl-coumarin | HCID 23334059 | 73% |
Reaction Steps
10 g. (0.042 mol) of 3-phenyl-4-hydroxy-coumarin and 10.1 g. (0.55 mol) of 2-piperidino-1-chlorethane hydrochloride are caused to react in the manner described in Example 1. 10.8 g. of a yellow oil are obtained, which cannot be crystallised. Yield 73% (theoretical yield 14.7 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230850 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-db9bb989ae1e480383e309cd738dd86d |
| Source note | uspto-grants-1980_10 |