Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 904291Generated: October 30, 2026

3-(Dimethylamino)propyl chloride hydrochloride → 4-(3'-Dimethylaminopropoxy)-3-phenyl-coumarin

https://huagongshe.com/reaction/904291

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Dimethylamino)propyl chloride hydrochlorideHCID 94308—
ReactantCoumarin, 4-hydroxy-3-phenyl-HCID 54688870—
Product4-(3'-Dimethylaminopropoxy)-3-phenyl-coumarinHCID 2333403159%

Reaction Steps

By treating 10 g. (0.042 mol) of 3-phenyl-4-hydroxy-coumarin with 87 g. (0.055 mol) of 3-dimethylamino-1-chloropropane hydrochloride as described in Example 1, there are obtained 8.1 g. of a yellow oil which cannot be crystallised. Yield 59% (theoretical yield 13.6 g.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04230850
Source datasetuspto-grants-1980_10
ORD IDord-21f0102d5124460a958c16ccd79fcf08
Source noteuspto-grants-1980_10