4-(2-Chloroethyl)morpholine → HCID 23334087, compound

HRID 904292Notes

Reaction equation

HRID 904292 reaction equation
[CH2:1]([C:5]1[C:6](=[O:18])[O:7][C:8]2[C:13]([C:14]=1[OH:15])=[C:12]([OH:16])[CH:11]=[C:10]([OH:17])[CH:9]=2)[CH2:2][CH2:3][CH3:4].[O:19]1[CH2:24][CH2:23][N:22]([CH2:25][CH2:26]Cl)[CH2:21][CH2:20]1>C(O)C>[CH2:1]([C:5]1[C:6](=[O:18])[O:7][C:8]2[C:13]([C:14]=1[O:15][CH2:26][CH2:25][N:22]1[CH2:23][CH2:24][O:19][CH2:20][CH2:21]1)=[C:12]([O:16][CH2:26][CH2:25][N:22]1[CH2:23][CH2:24][O:19][CH2:20][CH2:21]1)[CH:11]=[C:10]([O:17][CH2:26][CH2:25][N:22]1[CH2:23][CH2:24][O:19][CH2:20][CH2:21]1)[CH:9]=2)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 767274-(2-Chloroethyl)morpholineHCID 547213373-Butyl-4,5,7-trihydroxy-2H-1-benzopyran-2-one

Product 1

HCID 23334087HCID 23334087, compoundYield 45%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

7.5 g. (0.03 mol) of 3-butyl-4,5,7-trihydroxy-coumarin are treated with 17.5 g. (0.117 mol) of 2-morpholino-1-chlorethane, as in Example 1. A beige-coloured solid is obtained. M.P. 131° C. (ethanol). Weight 7.7 g.; yield 45% (theoretical yield 17.7 g.).

Workup

  1. customA beige-coloured solid is obtained

Sources & evidence

ORD record
ord-1ff4d327cff146cf80713ad1db98a568
Source dataset
uspto-grants-1980_10
Patent number
US04230850

Reaction notes

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