HCID 22226923, compound → HCID 23334097, compound

HRID 904297Notes

Reaction equation

HRID 904297 reaction equation
[C:1]1([C:7]2[C:8](=[O:18])[O:9][C:10]3[CH2:11][CH2:12][CH2:13][CH2:14][C:15]=3[C:16]=2[OH:17])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:19]1[CH2:24][CH2:23][N:22]([CH:25](Cl)[CH3:26])[CH2:21][CH2:20]1>C(O)C>[O:19]1[CH2:24][CH2:23][N:22]([CH2:25][CH2:26][O:17][C:16]2[C:15]3[CH2:14][CH2:13][CH2:12][CH2:11][C:10]=3[O:9][C:8](=[O:18])[C:7]=2[C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH2:21][CH2:20]1

Participants

4

Reactant 2

HCID 22226923HCID 22226923, compoundHCID 547213304-Hydroxy-3-phenyl-5,6,7,8-tetrahydrocoumarin

Product 1

HCID 23334097HCID 23334097, compoundYield 71%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The desired product is prepared according to the method of Example 9 from 14.5 g. (0.06 mol) of 3-phenyl-4-hydroxy-5,6,7,8-tetrahydro-coumarin and 11.7 g. (0.078 mol) of 2-morpholino-2-chlorethane. M.P. 115° C. (ethanol); weight 15.1 g. (yield 71%, theoretical yield 21.3 g.).

Sources & evidence

ORD record
ord-a4d53b15820e4a67b8403dc379a39407
Source dataset
uspto-grants-1980_10
Patent number
US04230850

Reaction notes

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