HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Chloroethyl)morpholine → 4-(2'-Morpholinoethoxy)-3-phenyl-6-methoxy-coumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Chloroethyl)morpholine | HCID 76727 | — |
| Reactant | 4-Hydroxy-6-methoxy-3-phenyl-2H-1-benzopyran-2-one | HCID 54705896 | — |
| Product | 4-(2'-Morpholinoethoxy)-3-phenyl-6-methoxy-coumarin | HCID 23334084 | 67.5% |
Reaction Steps
This compound is obtained according to the method of Example 8 from 12.1 g. (0.045 mol) of 6-methoxy-3-phenyl-4-hydroxy-coumarin and 10.9 g. (0.057 mol) of 2-morpholino-1-chlorethane. After recrystallisation from isopropanol, 11.3 g. of a beige-coloured solid are obtained. M.P. 118° C.; yield 67.5% (theoretical yield 16.7 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230850 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-7ff36042058c4a20abbe513115454e47 |
| Source note | uspto-grants-1980_10 |