Diethylaminoethyl chloride → HCID 23334096, compound

HRID 904314Notes

Reaction equation

HRID 904314 reaction equation
[OH:1][C:2]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[O:5][C:4](=[O:12])[C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[CH2:19]([N:21]([CH2:25][CH3:26])[CH2:22][CH2:23]Cl)[CH3:20]>>[CH2:19]([N:21]([CH2:25][CH3:26])[CH2:22][CH2:23][O:1][C:2]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[O:5][C:4](=[O:12])[C:3]=1[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1)[CH3:20]

Participants

3

Reactant 2

HCID 13364Diethylaminoethyl chlorideHCID 547213304-Hydroxy-3-phenyl-5,6,7,8-tetrahydrocoumarin

Product 1

HCID 23334096HCID 23334096, compoundYield 68.7%

Procedure

Prepared as indicated in Example 14, Stage B, from 12.1 g. (0.05 mol) of 4-hydroxy-3-phenyl-5,6,7,8-tetrahydrocoumarin (Example 14, Stage A) and 8.8 g. (0.065 mol) of 2-diethylamino-1-chloroethane. 13.2 g. of an oil are obtained, which cannot be crystallised. Yield 68.7% (theoretical yield 19.2 g.).

Workup

  1. customPrepared
  2. customof an oil are obtained
  3. customwhich cannot be crystallised

Sources & evidence

ORD record
ord-d8c7577769064dc79837dfa8ce0ed708
Source dataset
uspto-grants-1980_10
Patent number
US04230850

Reaction notes

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