HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-Chloro-2-methylpropyl)morpholine → 4-(3'-Morpholino-2'-methylpropoxy)-3-phenyl-8-hydroxy-coumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-Chloro-2-methylpropyl)morpholine | HCID 23334047 | — |
| Reactant | 3-Phenyl-4,8-dihydroxy-coumarin | HCID 54721333 | — |
| Product | 4-(3'-Morpholino-2'-methylpropoxy)-3-phenyl-8-hydroxy-coumarin | HCID 23334091 | 60.7% |
Reaction Steps
Prepared according to the method of Example 30 by alkylation of 4,8-dihydroxy-3-phenyl-coumarin by 1-chloro-2-methyl-3-morpholino-propane. After recrystallisation from isopropanol, a white solid is obtained with the melting point of 136° C. Yield 60.7%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230850 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-4adcc4ba253e4b3eb26db3ec8bec4423 |
| Source note | uspto-grants-1980_10 |