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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 904328Generated: October 31, 2026

4-(3-Chloro-2-methylpropyl)morpholine → 4-(3'-Morpholino-2'-methylpropoxy)-3,8-diphenyl-coumarin

https://huagongshe.com/reaction/904328

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Chloro-2-methylpropyl)morpholineHCID 23334047—
Reactant4-hydroxy-3,8-diphenyl-2H-chromen-2-oneHCID 54688869—
Product4-(3'-Morpholino-2'-methylpropoxy)-3,8-diphenyl-coumarinHCID 2333408869.1%

Reaction Steps

Prepared according to the method of Example 8, by alkylation of 4-hydroxy-3,8-diphenyl-coumarin with 3-morpholino-2-methyl-1-chloropropane. After recrystallisation from ethanol, a solid melting at 120°-121° C. is obtained. Yield 69.1%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04230850
Source datasetuspto-grants-1980_10
ORD IDord-7df5728bec874eb1a472d5ecd0c9dfc7
Source noteuspto-grants-1980_10