Aluminium lithium hydride → HCID 178519987, compound

HRID 904387Notes

Reaction equation

HRID 904387 reaction equation
[OH:1][C:2]1[C:3]([C:8](O)=[O:9])=[N:4][CH:5]=[CH:6][N:7]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[OH:1][C:2]1[C:3]([CH2:8][OH:9])=[N:4][CH:5]=[CH:6][N:7]=1

Participants

4

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 178524895HCID 178524895, compound

Product 1

HCID 178519987HCID 178519987, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

3-Hydroxypyrazine-2-carboxylic acid is converted to the corresponding ethyl ester and the ester is reduced with lithium aluminium hydride in tetrahydrofuran to give 3-hydroxy-2-hydroxymethylpyrazine.

Sources & evidence

ORD record
ord-481d92a8aa2442a092147ed8a1dafbf3
Source dataset
uspto-grants-1980_10
Patent number
US04230865

Reaction notes

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