Sodium Hydroxide → HCID 178507192, compound

HRID 904635Notes

Reaction equation

HRID 904635 reaction equation
[CH2:1]1[O:17][C:16]2[C:3](=[CH:4][C:5]([N+:18]([O-])=O)=[C:6]([CH:15]=2)[C:7]([NH:9][C:10]2[NH:14][N:13]=[N:12][N:11]=2)=[O:8])[O:2]1.[OH-].[Na+]>[Pd].O>[NH2:18][C:5]1[CH:4]=[C:3]2[O:2][CH2:1][O:17][C:16]2=[CH:15][C:6]=1[C:7]([NH:9][C:10]1[NH:11][N:12]=[N:13][N:14]=1)=[O:8]

Participants

5

Reactant 2

HCID 14798Sodium HydroxideHCID 178522647HCID 178522647, compound

Product 1

HCID 178507192HCID 178507192, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 962WaterSolvent

Procedure

Hydrogenation of 10 g of 4,5-methylenedioxy-2-nitro-N-(1H-tetrazol-5-yl)benzamide in 40 ml of aqueous 1N sodium hydroxide solution and 160 ml of water and using 1 g of 10% Pd/C gave 2-amino-4,5-methylenedioxy-N-(1H-tetrazol-5-yl)benzamide as brown needles melting at about 255° C. (dec) after recrystallization from a mixture of dimethylformamide and water.

Sources & evidence

ORD record
ord-125dca14cf9145c8936fbc132b17a9af
Source dataset
uspto-grants-1983_12
Patent number
US04419357

Reaction notes

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