反应详情

The product of step (b) (3 g, 0.0099 mole) was dissolved in dry benzene (50 mls), treated with phosphoryl chloride (2.5 mls) and refluxed for 1 hour. The reaction mixture was cooled, poured into water and extracted with ether, which was then washed with water and dried over magnesium sulphate. The solvent was evaporated to leave 2.8 g of yellow-brown solid. Recrystallisation from cyclohexane gave yellow needles mp 163°-164°.

1. temperaturerefluxed for 1 hour
2. temperatureThe reaction mixture was cooled
3. extractionextracted with ether, which
4. washwas then washed with water
5. dry with materialdried over magnesium sulphate
6. customThe solvent was evaporated