Calcium nitrate → Calcium 6-chloro-4-oxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylate

HRID 904679Notes

Reaction equation

HRID 904679 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([CH2:20][CH2:21][CH3:22])[C:8]3[O:15][C:14]([C:16]([O-:18])=[O:17])=[CH:13][C:12](=[O:19])[C:9]=3[CH:10]=2)[N:5]=[C:4]([C:23]([O-:25])=[O:24])[CH:3]=1.[Na+].[Na+].[N+]([O-])([O-])=O.[Ca+2:32].[N+]([O-])([O-])=O>O.CO>[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([CH2:20][CH2:21][CH3:22])[C:8]3[O:15][C:14]([C:16]([O-:18])=[O:17])=[CH:13][C:12](=[O:19])[C:9]=3[CH:10]=2)[N:5]=[C:4]([C:23]([O-:25])=[O:24])[CH:3]=1.[Ca+2:32]

Participants

5

Reactant 2

HCID 24963Calcium nitrateHCID 30365866-chloro-4-oxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylate

Product 1

HCID 20478385Calcium 6-chloro-4-oxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylateYield 221.6%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

Disodium 6-chloro-4-oxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylate (0.5 g) was dissolved in water (1 ml) and a solution of anhydrous calcium nitrate (0.05 g) in methanol (5 ml) was added. After stirring for one hour the precipitate was collected and washed well with water. Drying in vacuo at 50° C. afforded the title compound (0.27 g) as a yellow solid.

Workup

  1. customwas collected
  2. washwashed well with water
  3. customDrying in vacuo at 50° C.

Sources & evidence

ORD record
ord-b8482112a5384b4fb860991818261ba5
Source dataset
uspto-grants-1983_12
Patent number
US04419352

Reaction notes

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