Formaldehyde → ST4016777

HRID 904784Notes

Reaction equation

HRID 904784 reaction equation
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[P:7]([O-:14])([O:11][CH2:12][CH3:13])[O:8][CH2:9][CH3:10].[CH2:15]=O>>[O:4]1[CH2:5][CH2:6][N:1]([CH2:15][P:7](=[O:14])([O:11][CH2:12][CH3:13])[O:8][CH2:9][CH3:10])[CH2:2][CH2:3]1

Participants

4

Reactant 3

HCID 712FormaldehydeHCID 8083MorpholineHCID 3780918Diethylphosphite

Product 1

HCID 520307ST4016777

Procedure

To a stirred mixture of morpholine (43.5 g:0.5 mole) and diethyl phosphite (69 g:0.5 mole) was added aqueous formaldehyde (41 g:0.5 mole) during 60 min. at 50°-60°. After stirring for an additional 1 hr. water was removed in vacuo and the resulting oil distilled. Pure diethyl morpholinomethylphosphonate, 105 g (87%) bp 108°-9°/0.1 mm was obtained.

Workup

  1. customwater was removed in vacuo
  2. distillationthe resulting oil distilled

Sources & evidence

ORD record
ord-f3924a1eee784d38b9d406f98985c373
Source dataset
uspto-grants-1983_12
Patent number
US04420399

Reaction notes

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