2-Hydroxybutanedioic acid--lysine (1/1) → HCID 131713241, compound

Participants

Reaction Steps

In the same manner as described in Example 5, there is obtained an aqueous solution (185.3 g) of neutral L-lysine L-malate (concentration of the neutral L-lysine L-malate: 50% by weight). To a stirring vessel containing ethanol (500 ml) is gradually added the solution of neutral L-lysine L-malate obtained above to precipitate crystals well. The precipitated crystals are collected by filtration and air-dried at 40° C. overnight to give neutral L-lysine L-malate monohydrate (94 g, yield: 93.0%).

Provenance & Evidence